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Rozerem  (ramelteon 8-mg tablets)                                          01/07                              

From: Takeda Pharmaceuticals to RxLink Pharmacy

What can you tell your Rozerem customers to expect?

Dear RxLink Pharmacist: 

The perception patients have of how a sleep medicine works may not be the reality with Rozerem. For example, patients may think that because the don't feel sedated, Rozerem isn't working. But because Rozerem targets the nromal sleep-wake cycle to initate sleep, this isn't the case. So, it may be important for patients to know what to expect from Rozerem.

Enclosed is a brochure that can help guide you in educating your customers about Rozerem. It explains what you can tell them to expect from Rozerem.

In addition, the brochure lists many key features of Rozerem. To learn more about Rozerem, go to www.rozerem.com. Please see important safty information on the back of this letter. If you have additional questions concerning Rozerem, please contact your Tekeda Sales Represenitive or call 1-877-TAKEDA-7

 

Sincerely,

Mike Krohn

Product Manager, Neuroscience Marketing 

Takeda Pharmaceuticals North America, Inc.

 

Important Safety Infromation

Rozerem is indecated for the treatment of insomnia characterized by difficulty with sleep onset. Rozerem can be prescribed for long-term use. Rozerem should not be use in paitents with hypersensitivity to any components of the formulation, severe hapatic impairment, or combination with fluvoxamine. Failure of insomnia to remit after a reasonable period of time should be medically evaluated, as this may be a result of an unrecognized underlying medical disorder. Hypontics should be administered with caution to patients exhibiting signs and symptoms of depression. Rozerem has not been stuided inpatients with severe sleep apnea, severe COP, or in children or adolescents. The effects in these populations are unknow. Aviod taking Rozerem with alcohol. Rozerem has been associated with decreased testosterone levels and increased prolactin levels. Health professionals should be mindful of any unexplained symptoms possibly associated with such changes in these hormone levels. Rozerem should not be taken with or immediately after a high-fat meal. Rozerem should be taked within 30 minutes before going to bed and activities confined to preparing for bed. The mosy common adverse events seen with Rozerem that had at least a 2% incidence difference from placebo were somnolence,dizziness, and fatigue. 


RxLink, LLC   2007   

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